MabSelect Xtra, Cytiva, 17-5269-02, pack of 200 mL

Code: GE17-5269-02 D2-231

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Application

MabSelect™ Xtra has...


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€7,432.80 EACH
€9,142.34 inc. VAT
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Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Application

MabSelect™ Xtra has the same recombinant Protein A ligand as MabSelect™ but is based on a high-fLow Agarose base matrix with increased porosity and a slightly decreased particle size compared to MabSelect. This results in higher capacity—MabSelect™ Xtra has about 30% higher dynamic binding capacity for IgG than currently available Protein A chromatography media. In addition, MabSelect™ Xtra has a higher capacitiy for many Fc-fusion Proteins.The medium provides a lower overall production cost due to the possibility of processing concentrated feedstocks in fewer batches.MabSelect™ Xtra is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, MabSelect™ Xtra meets industrial demands with security of supply and comprehensive technical and regulatory support.

Features and Benefits

Higher dynamic binding capacity than currently available Protein A chromatography media. Improved process economics through reduced raw materials costs and/or reduced number of cycles High purity capture due to high ligand selectivity and matrix hydrophilicity Slightly lower pressure/fLow properties compared to MabSelect™ SuRe™ and MabSelect

General description

MabSelect™ Xtra, with extra high dynamic binding capacity, is a member of the MabSelect™ family. Developed to meet the demands of increasing levels of expression in monoclonal antibody feedstocks.

Legal Information

SuRe is a trademark of Cytiva

MabSelect is a trademark of Cytiva

avg. part. size75 (d??v is the median particle size of the cumulative volume distribution)
capacity≥30 mg binding capacity (humanlgG/ml at 2.4 min residence time)(Determined at 10% breakthrough by frontal analysis at a mobile phase velocity of 500 cm/h in a column with a bed height of 20 cm.)
cleaning in place2-12(pH below 3 is sometimes required to elute strongly bound IgG species. However, protein ligands may hydrolyze at very low pH.)
manufacturer/tradenameCytiva 17-5269-02
matrixhighly cross-linked agarose
packagingpack of 200 mL
shelf lifePlease be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
storage condition(20% Ehtanol)
storage temp.2-8°C
suitabilitysuitable for bioprocess medium
working range3-10(pH below 3 is sometimes required to elute strongly bound IgG species. However, protein ligands may hydrolyze at very low pH.)
This product has met the following criteria to qualify for the following awards:



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